exhaustion and pain that kept her on the couch much of the day. The 58-year-old Seattle speech coach didn’t want to take opioid pain-killers, but Tylenol wasn’t helping enough. Roth was intrigued when women in her online chat group enthused about a cannabis-derived oil called cannabidiol (CBD) that they said relieved pain without making them high. So Roth, who hadn’t smoked weed since college but lived in a state where cannabis was legal, walked into a dispensary and bought a CBD tincture. “Within a few hours of placing the drops in my mouth, the malaise and achiness that had plagued me for weeks lifted and became much more manageable,” she says. She took the drops several times a day and in a few weeks was back to her regular life.
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Cannabinol results from the degradation of THC. There is little of it in the fresh plant, but decarboxylation often raises the amount of CBN in the plant as an effect. CBN is only mildly psychoactive and has a higher affinity for the CB2 receptor than the CB1 receptor, linking CBN to the body’s immune system. In hemp oil, CBN is present in levels of 0.2% or lower.
Being a relatively inexpensive method it is preferred by small scale producers of CBD and THC oils. During extraction this method uses solvents like butane, ethanol and alcohol derived from grains. This method has several disadvantages the worst of which is potential of explosion while the second is leftover residue of these solvents. Scientists and doctors advice against the use of this method as it can make the end product unsafe for medical use and also can make existing medical condition much worse. When there are unsafe residues in CBD oil it reduces healing powers and can even compromise health of patients.
Herrera and her patients aren't the only ones doling out rave reviews for CBD oil, which can be found online and in cannabis dispensaries, as well as in some grocery stores and even as an optional add-in alongside protein powder at your local juice chain. The oil has been riding the coattails of the growing legal cannabis industry, with one industry expert, Matt Karnes, telling Forbes in 2016 that he expected CBD products to become an almost $3 billion market by 2021.

Cannabinol results from the degradation of THC. There is little of it in the fresh plant, but decarboxylation often raises the amount of CBN in the plant as an effect. CBN is only mildly psychoactive and has a higher affinity for the CB2 receptor than the CB1 receptor, linking CBN to the body’s immune system. In hemp oil, CBN is present in levels of 0.2% or lower.


So, many of CBD's popularized benefits aren't well-proven. But are there any harms in trying CBD-containing products? In a word, yes. While any reported side effects from CBD alone are minor (think dry mouth and dizziness), they can be serious if the CBD products interact with other medications, experts say. Since CBD is metabolized by the same enzyme in the liver that metabolizes many conventional medicines and supplements, the chemical can cause the levels of other drugs in the system to rise; in some cases – like for those taking a drug to prevent their bodies from rejecting a donor organ – to a deadly level, Tishler says.
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The most abundant cannabinoid in hemp oil, making up over 90% of the cannabinoid content, cannabidiol or CBD is non-psychoactive and is the focus of the benefits from hemp oil. CBD has little affinity for CB1 or CB2 receptors, the main points of interaction for cannabinoids in the endocannabinoid system, and instead acts as an indirect antagonist of cannabinoid agonists, possibly allowing CBD to temper the high caused by THC. Our Gold Label RSHO™ is almost 25% CBD, making up most of oil’s weight. All other cannabinoids come in under 0.4% by weight.
You need a series of chambers for CO2 extraction. Their role is to control pressure and temperature. The pressure and temperature in the chambers force the CO2 cannabinoid solution to react with one another and then separate. As the cannabinoids separate, the chambers collect them separately. The extractor can then choose which cannabinoids to put into their product or products.
Full spectrum (or “whole plant”) products contain CBD as well as terpenes and other cannabinoids such as CBG, CBN and trace amounts of THC. Usually these will be in ratios that were naturally-occurring and extracted from the plant and specific strain. Terpenes and cannabinoids are occasionally added back into products as an isolated form to raise the potency of the product.
Along with its better-known counterpart, THC (delta-9-tetrahydrocannabinol, the chemical that produces the marijuana high), CBD is one of more than 400 compounds found in the oils of cannabis plant species, which include marijuana and hemp. Unlike THC, CBD will not make you high. That said, this doesn’t mean CBD is not at all psychoactive, as many assert, says Jahan Marcu, Ph.D., director of experimental pharmacology and behavior at the International Research Center on Cannabis and Mental Health in New York City: “CBD does change cognition. It affects mood, which is why people take it for anxiety. And some find that it makes them more alert.”
The key difference between hemp and marijuana is that hemp contains practically zero THC. In fact, in order to be classified as hemp, a cannabis plant must contain less than 0.3% THC by volume. This is really important because it’s actually the reason why hemp products are legal to buy, sell, and ship. If they don’t get you high, then why would they be illegal?
And without high-quality trials, experts don’t know how much is best for a given purpose. The staff at Roth’s dispensary told her, “Try some once or twice a day and see what happens.” (Half a dropper’s worth was a good amount for her.) One thing scientists feel confident about is that CBD is not dangerous. It won’t damage vital organs even at doses as high as 5,000 mg a day, Marcu says, and nobody has died from simply overdosing on a cannabis product.
To make matters more confusing, nine states (including California, Washington, and Colorado) let residents buy cannabis-based products with or without THC. Nearly two dozen other “medical marijuana states” allow the sale of cannabis, including capsules, tinctures, and other items containing CBD or THC, at licensed dispensaries to people whose doctors have certified that they have an approved condition (the list varies by state but includes chronic pain, PTSD, cancer, autism, Crohn’s disease, and multiple sclerosis). Sixteen more states legalized CBD for certain diseases. But because all these products are illegal according to the federal government, cannabis advocates are cautious. “By and large, the federal government is looking the other way,” says Paul Armentano, deputy director of the Washington, DC–based National Organization for the Reform of Marijuana Laws (NORML), but until federal laws are changed, “this administration or a future one could crack down on people who produce, manufacture, or use CBD, and the law would be on its side.”

There are a number of potential solvents that can be used to extract CBD oil from the hemp plant. Some companies choose to use dangerous chemical solvents in their extraction process. However, this opens the end user to residual contamination from any solvent that is left unpurged from the oil. To extract our CBD oil from our hemp crops, we use supercritical CO2.
PLEASE NOTE: if you are located in the USA with an order of $500.00 or more, or if you are an international customer with an order of $350.00 or more, we will need an order confirmation (by phone or email) stating that you approve of this purchase. This additional step is for your protection. You can expect an email from one of our customer service representatives regarding this - or please free to email us with your order number and purchase confirmation to [email protected]
In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.
Do the right thing for your body and ensure that you only purchase high-quality products from trusted sellers. Once you’ve decided between full spectrum vs regular CBD, you now need to make the choice of picking the right seller. Choose someone with a great reputation and independent lab testing results available on the site for all to see. You certainly want to make sure you get what you pay for! 

CBD—or cannabidiol—is a type of cannabinoid, a family of molecules typically associated with marijuana, but in fact, also found in other plants and even humans (in us, they’re called endocannabinoids). There are hundreds of different cannabinoids in marijuana. The best known is tetrahydrocannabinol, or THC, a chemical in marijuana that targets and binds to certain receptors in the brain to give you a high. CBD is non-psychoactive and non-addictive, and it seems to bind to multiple target sites, thereby affecting a range of systems throughout the body.

Miller, whose clients include patients referred by physicians, uses CBD in a variety of delivery modalities that she has found effective. “Patches can be worn for pain or anxiety management. Capsules or concentrated drops can be taken orally for pain, inflammation, sleep, and anxiety. Balms and creams can be used on the hands and feet to manage arthritic pain. Vaping is another delivery method,” she says.


There's also the question of CBD's legality – something that's a lot grayer than the black-and-white picture most companies paint. The U.S. Drug Enforcement Administration considers CBD, like all cannabinoids, a schedule 1 drug. That means it's just as illegal as heroin and ecstasy. Meanwhile, hemp – a variety of the cannabis plant regulated by the U.S. Department of Agriculture – is legal , so long as its THC content is negligibly low. But because the agriculture department doesn't test for CBD – only THC – in hemp, more companies are getting away with selling products they say contain CBD, says Sara Jane Ward, an assistant professor of pharmacology at the Temple University Lewis Katz School of Medicine who's been studying CBD in rodent models for more than 10 years. Needless to say, the legality of CBD is "very confusing and very gray," she says.
In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.
Yes: CBD extracts can’t always be trusted. A 2017 JAMA paper reported that almost 70 percent of all CBD products sold online do not contain the amount of CBD stated on the label. Of the 84 products bought from 31 different companies, 42 percent contained a higher concentration of CBD oil than the label claimed, and 26 percent of the products contained less than the label claimed. The remainder of products contained the labeled amount—give or take 10 percent.
You need a series of chambers for CO2 extraction. Their role is to control pressure and temperature. The pressure and temperature in the chambers force the CO2 cannabinoid solution to react with one another and then separate. As the cannabinoids separate, the chambers collect them separately. The extractor can then choose which cannabinoids to put into their product or products.

CBD is one of over 110 active cannabinoids inside marijuana plants and is most predominant inside the resin glands (trichomes) of the female cannabis plant. Your body contains cell receptors known as cannabinoid receptors. Cannabinoids, found in cannabis, are agonists that bind to these receptors. Cannabinoid receptors can be found all over the body including, but not limited to, the:
Essential fatty acids are necessary for maintaining heart and cardiovascular health. The two primary essential fatty acids — Omega 3 and Omega 6 — are ideally consumed at a ratio of around 3:1. Unfortunately, in the typical American diet, that ratio is close to 25:1. Full-spectrum hemp oil offers the two essential fatty acids in the optimal 3:1 ratio.

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Immediately after reading this article I realized this is not the difference I was expecting.  While the USDA says that it takes a chemical analysis to tell the difference between hemp and medical marijuana, for most of us it would only take 2 seconds to notice the difference between a field of hemp and a medical marijuana grow operation.  As far as definition is concerned the two are not so far off from one another. Hemp and marijuana are both cannabis and it would seem that the only real difference is that “marijuana” or more recent term “medical marijuana” is classified as a variety of cannabis with a high percent of THC and, occasionally, high CBD as well.
While there is much debate on which form is better, this 2015 study leans in favor of full spectrum CBD oil products. There are many that believe that other cannabinoids, THC especially, are necessary to take full advantage of what cannabis has to offer. Ultimately, however, we are all different and it comes down to the individual user and their needs. If drug testing is a concern, you’re encouraged to seek out CBD isolate products (or terpsolates) or broad spectrum products instead of full spectrum.
Supercritical CO2 extraction is also the key to understanding more cannabinoids in cannabis like Cannabichromene (CBC) and cannabicitran (CBT) and how they interact with each other (called the Entourage effect). This can lead to increased understanding of marijuana in the medical field, and will also allow growers to come up with more effective, new and exciting strains.
CBD and THC interact with our bodies in a variety of ways. One of the main ways they impact us is by mimicking and augmenting the effects of the compounds in our bodies called “endogenous cannabinoids” - so named because of their similarity to the compounds found in the cannabis plant. These “endocannabinoids” are part of a regulatory system called the “endocannabinoid system”.
Instead, the human body manages cannabinoids through its endocannabinoid system, also known as ECS, which can process CBD and hemp oil through the body and is managed by the human brain, which uses cannabinoids to regulate the body's physiological reactions to the herb, and help better manage key human elements like eating, sleeping, dealing with pains and illnesses, and improving mood.
PLEASE NOTE: if you are located in the USA with an order of $500.00 or more, or if you are an international customer with an order of $350.00 or more, we will need an order confirmation (by phone or email) stating that you approve of this purchase. This additional step is for your protection. You can expect an email from one of our customer service representatives regarding this - or please free to email us with your order number and purchase confirmation to [email protected]

"If it proved effective for anxiety, depression and panic disorder, it may have other effects as well that could be useful and beneficial [but] this is a really early stage," says David Shurtleff, the acting director of the National Center for Complementary and Integrative Health. His organization's stance: "Take it one step at a time and do the work and really state where we are right now with the research," he says.
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