Although CBD oils aren’t regulated by the FDA, purchasing products stateside from one of the nine states where recreational and medical cannabis use is legal will likely result in a higher-quality product than buying one made with hemp-derived CBD oil imported from abroad, says Martin Lee, director of Project CBD, a nonprofit that promotes medical research into CBD.

The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide far better performance than any single compound alone, and that includes CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
Keep in mind, too, that CBD product companies use different CBD sources, extraction methods and production techniques – and not all resulting products are created equal. You'll have to do your own research to determine which companies you're willing to trust, Asquith says. Plus, how the products are packaged and consumed – be they in oils, creams or capsules – affect how they're absorbed in the body. Edibles, for example, are well-absorbed, while oils taken under the tongue are "baloney," Tishler says. And of course, salespeople at herb shops don't have the same mission, knowledge, training or oversight as physicians and pharmacists. "We have spent the last 100 years or so developing the pharmaceutical system because it works," Tishler says.
With that being said, let’s discuss the wonderful thing we call CBD oil. CBD, cannabidiol, is one of over 85 active cannabinoids identified in hemp and other cannabis plants. CBD oil is derived from hemp, due to its abundance naturally occurring in the plant. CBD oil is extracted using the whole plant, stalks or flowers. Since hemp contains only trace amounts of THC, CBD oil products are non-intoxicating. 
There are more than 80 cannabinoids found in cannabis plants, with THC being the primary one, followed by CBD. However, in the hemp plant, which is a different strain of the species Cannabis sativa, CBD is the main active ingredient, and THC is barely present, making its use and legality more widespread. The reason that CBD is such an effective form of support for human health is due to the body’s endogenous cannabinoid system. This regulatory structure of the body has millions of cannabinoid receptors in the brain and nervous system, which react not only to plant-derived cannabinoids (such as hemp and marijuana) but also to natural cannabinoids produced within our body. When hemp oil is used and processed by the body, it is effectively boosting the function of the endocannabinoid system, helping our body regulate itself in many different ways.
You need a series of chambers for CO2 extraction. Their role is to control pressure and temperature. The pressure and temperature in the chambers force the CO2 cannabinoid solution to react with one another and then separate. As the cannabinoids separate, the chambers collect them separately. The extractor can then choose which cannabinoids to put into their product or products.

Scott Shannon, M.D., assistant clinical professor at the University of Colorado, recently sifted through patient charts from his four-doctor practice to document CBD’s effects on anxiety. His study, as yet unpublished, found “a fairly rapid decrease in anxiety scores that appears to persist for months,” he says. But he says he can’t discount a placebo effect, especially since “there’s a lot of hype right now.”

Like we mentioned a moment ago, it used to be the belief that “pure CBD,” or CBD isolate, packed the most potent punch in terms of cannabis therapy. And that would make sense too, right? If we know that CBD is primarily the active compound in the plant that provides the medical relief and therapy, then wouldn’t it make sense to make a 100% pure powder out of it?

Recently I asked myself this very question and the more I read the more contradictory statements I found and the more confused I became. With an extensive background in medical marijuana and high THC strains I felt I had a good grasp on which one was “better” before I started researching for this article and could make a good argument for why medical marijuana derived CBD is better than hemp derived CBD.  More recently I have been introduced to CBD derived from hemp and after some preliminary research I was not so sure. Fortunately, I have connections from within the industry and so my mission began. I set out to talk to the largest names on both sides of the spectrum and get their opinions on this matter.
Our commitment to product quality and purity has driven HempMeds® to develop the strictest testing process in our industry, the Triple Lab Tested™ standard. We use ISO/IEC 17025:2005 accredited testing labs to examine our hemp oil and assure both its safety and consistency. These labs test our hemp oil for the concentration of cannabinoids, including CBD, CBDa, CBG, THC, and over a half dozen others. By testing our hemp oil three times during our process, we ensure that our products are completely safe for use by you and your entire family.
The cannabidiol oil is derived from flowers of cannabis plants and is concentrated in its resin glands or trichomes. These glands contain oil that is rich in CBD which differs in quality and quantity between different strains of the cannabis plant. The active CBD available in the flower can be purified and concentrated using precise production techniques. When oil of high potency and concentration is derived from the glands then it can be used in lesser dosage. This lesser dosage saves money as CBD oil is an expensive product but produces the desired effect.
The benefits of cannabidiol are being studied thoroughly. As of now, we know that CBD works positively with our endocannabinoid system, which is responsible for keeping our body in homeostasis (balance). Cannabidiol reacts with the cannabinoid receptors to maintain that balance. CBD oil products are used for their effects ranging from soothing sore muscles and joints, inflammation, calming, promoting more restful sleep and more.

There are a number of potential solvents that can be used to extract CBD oil from the hemp plant. Some companies choose to use dangerous chemical solvents in their extraction process. However, this opens the end user to residual contamination from any solvent that is left unpurged from the oil. To extract our CBD oil from our hemp crops, we use supercritical CO2.
So, many of CBD's popularized benefits aren't well-proven. But are there any harms in trying CBD-containing products? In a word, yes. While any reported side effects from CBD alone are minor (think dry mouth and dizziness), they can be serious if the CBD products interact with other medications, experts say. Since CBD is metabolized by the same enzyme in the liver that metabolizes many conventional medicines and supplements, the chemical can cause the levels of other drugs in the system to rise; in some cases – like for those taking a drug to prevent their bodies from rejecting a donor organ – to a deadly level, Tishler says.
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With that being said, let’s discuss the wonderful thing we call CBD oil. CBD, cannabidiol, is one of over 85 active cannabinoids identified in hemp and other cannabis plants. CBD oil is derived from hemp, due to its abundance naturally occurring in the plant. CBD oil is extracted using the whole plant, stalks or flowers. Since hemp contains only trace amounts of THC, CBD oil products are non-intoxicating. 
There are a number of possible side effects to using CBD oil, such as fatigue, dry mouth, lightheadedness, hypotension, and impaired motor functions. However, when used in moderate amounts, most people do not experience these side effects, and none of them are known for being fatal or particularly dangerous. More than 20,000 studies have been done in the past 15 years on cannabis, hemp, and cannabinoids, and the results have been overwhelmingly supportive of the therapeutic potential and viability of CBD oil. That being said, some people should be cautious before using this powerful oil.
Researchers at the Department of Pharmacognosy, The School of Pharmacy, University of London, UK, basis the study conducted on mice found that CBD oil has analgesic properties and may relieve chronic pain of all kinds . It can disrupt the activity of pain receptors in the body and instead cause a release of neurotransmitters such as serotonin and dopamine – “feel good” compounds that can ease discomfort and pain, even if the pharmaceutical painkillers have no effect.
Being a relatively inexpensive method it is preferred by small scale producers of CBD and THC oils. During extraction this method uses solvents like butane, ethanol and alcohol derived from grains. This method has several disadvantages the worst of which is potential of explosion while the second is leftover residue of these solvents. Scientists and doctors advice against the use of this method as it can make the end product unsafe for medical use and also can make existing medical condition much worse. When there are unsafe residues in CBD oil it reduces healing powers and can even compromise health of patients.
Immediately after reading this article I realized this is not the difference I was expecting.  While the USDA says that it takes a chemical analysis to tell the difference between hemp and medical marijuana, for most of us it would only take 2 seconds to notice the difference between a field of hemp and a medical marijuana grow operation.  As far as definition is concerned the two are not so far off from one another. Hemp and marijuana are both cannabis and it would seem that the only real difference is that “marijuana” or more recent term “medical marijuana” is classified as a variety of cannabis with a high percent of THC and, occasionally, high CBD as well.

So which is better? Hemp derived CBD or Medical marijuana derived CBD?  I believe, given the information I have found, that the reasonable and definitive question we should ask is: What are the pros and cons of both options and, most of all, what will be best for me and fit my lifestyle. In addition, legality within the state and country you live must be taken into consideration. 
For example, it eases pain and inflammation. It can also help treat anxiety, epilepsy, and some types of cancer. These are just a few of its many benefits. CBD oil provides relief without the psychoactive effects created by THC. Without the buzz, there are more medical uses for the drug. In order to separate CBD from the THC and other parts of the plant, you have to extract it. The end product is CBD hemp oil.
CBD oil is not legal everywhere. It is banned/restricted by countries such as UAE, Dubai, and Saudi Arabia. Although CBD oil is illegal in many of the US states too, some have legalized its use for medicinal purposes. While the number would be ever-changing, as of 2016 there are 17 states in the US which have legalized the use of low THC, high CBD products for medical reasons in limited situations. These states include Alabama, Georgia, Iowa, Kentucky, Florida, Mississippi, Louisiana, Missouri, North Carolina, Oklahoma, South Carolina, Wisconsin, Wyoming, Tennessee, Texas, Utah, and Virginia. It is advisable to consult your local health specialist before use.
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So Herrera, who's experienced her own share of pain due to a shoulder injury followed by a bout of Lyme disease, went to a local herb shop and bought a vial of the oil, which, by some definitions, is legal in all states if it doesn't contain more than 0.3 percent THC – the psychoactive component of cannabis. She began putting seven to nine drops under her tongue first thing most mornings – and was startled by the results. "It's changed my pain level, my anxiety level and my stress level," says Herrera, who already practiced yoga, meditated regularly, ate a healthy diet and tried conventional medical treatments for pain and mobility. "It was shocking," she says, because she thought her patients' reports were due to the placebo effect. "Right now," she adds, "I feel pretty amazing."
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