‘The media has no doubt helped drive this popularity,’ says Dr Sarah Brewer, medical director at Healthspan. ‘However, the main drive is because people who take it experience the benefits very quickly, and “word of mouth” is a powerful thing. CBD oil also has such a wide range of benefits, reducing anxiety, promoting relaxation, ensuring a good night’s sleep, reducing pain perception and improving general feelings of wellbeing. It therefore appeals to a wide range of people.’
Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.
Do the right thing for your body and ensure that you only purchase high-quality products from trusted sellers. Once you’ve decided between full spectrum vs regular CBD, you now need to make the choice of picking the right seller. Choose someone with a great reputation and independent lab testing results available on the site for all to see. You certainly want to make sure you get what you pay for!
“What is CBD oil” may be your first question, but the real question we have to answer is, “What does CBD oil do?” CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. Like an acrobat on a highwire, as the environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to keep us level.
The plants are cultivated and then sent for extraction. Some CBD oil-based products come from whole plant extracts. Others are derived from isolates. Whole plant extraction is self-explanatory. The entire plant is part of the process. Those in the medical communities prefer this method. They believe that a broader spectrum of cannabinoids yields during whole plant extraction. According to medical specialists, capturing the entire cannabinoid spectrum stimulates the endocannabinoid system. They call this the “entourage effect.”
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, M.D., clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger. This is why Amanda Oliver, 31, a career consultant in Charleston, SC, pops a CBD gummy bear each night before bed. “I used to lie there tossing and turning as my mind raced from work projects to whether I had set the home alarm,” Oliver says. One piece of candy with 15 mg of CBD is enough to shut off her brain and facilitate sleep. She also swears by the CBD oil she takes at the height of her period, which she says quells her debilitating cramps.
Isolate CBD is the CBD gets its extraction from the cannabis plant without other terpenes and cannabinoids. Many users of this CBD type consider this much better than the full spectrum. They go as far enough to get this type of CBD by isolating the CBD from others themselves. They are even different dosage methods and levels for each kind of CBDs and therefore should carefully be in separation for each of the CBD types.
A study published by David Cheng, Postdoctoral Scientist, Neuroscience Research, University of New South Wales, NSW, Australia, says that CBD has a potential as a preventive measure against symptoms of Alzheimer’s. This presents yet another exciting development for medical researchers, given the persistent challenges to finding effective solutions for this condition.
And without high-quality trials, experts don’t know how much is best for a given purpose. The staff at Roth’s dispensary told her, “Try some once or twice a day and see what happens.” (Half a dropper’s worth was a good amount for her.) One thing scientists feel confident about is that CBD is not dangerous. It won’t damage vital organs even at doses as high as 5,000 mg a day, Marcu says, and nobody has died from simply overdosing on a cannabis product.
In another, a specific combination of CBD and other secondary cannabinoids were found to work together to slow tumor grown in cases of colon cancer. These sorts of synergistic effects are fairly common in whole plant extracts, and aren’t unique to cannabis. However, the sheer volume of active compounds in cannabis extracts, and their wide-ranging effects certainly distinguish them from other plants.