Considered the most scientific method this is also among the cleanest techniques of extraction. Referred to as sub-critical or super critical CO² method, it uses carbon dioxide under different pressures to extract the medicinal oil. This is among the most expensive techniques of extraction due to use of hi-tech equipment that can be operated by trained personnel only. The advantage of this technique is that the end product is the purest form of CBD oil which is highly potent and free of chlorophyll. However if the heat used during extraction is too high it can damage terpenes in the oil that have therapeutic benefits and provide flavor and essence to the oil strain.
There's also the question of CBD's legality – something that's a lot grayer than the black-and-white picture most companies paint. The U.S. Drug Enforcement Administration considers CBD, like all cannabinoids, a schedule 1 drug. That means it's just as illegal as heroin and ecstasy. Meanwhile, hemp – a variety of the cannabis plant regulated by the U.S. Department of Agriculture – is legal , so long as its THC content is negligibly low. But because the agriculture department doesn't test for CBD – only THC – in hemp, more companies are getting away with selling products they say contain CBD, says Sara Jane Ward, an assistant professor of pharmacology at the Temple University Lewis Katz School of Medicine who's been studying CBD in rodent models for more than 10 years. Needless to say, the legality of CBD is "very confusing and very gray," she says.

John Staughton is a traveling writer, editor, and publisher who earned his English and Integrative Biology degrees from the University of Illinois in Champaign, Urbana (USA). He is the co-founder of a literary journal, Sheriff Nottingham, and calls the most beautiful places in the world his office. On a perpetual journey towards the idea of home, he uses words to educate, inspire, uplift and evolve.

Given CBD’s reputation as a popular, artisanal remedy, one would think that Epidiolex would command a lot of “off label” attention. After all, physicians often prescribe pharmaceuticals off label to treat conditions that were not the actual focus of clinical trials. But the costly price tag for Epidiolex (more than $30,000 annually) precludes off label prescribing as well as affordable access for tens of millions of Americans without health insurance.
In isolate form, CBD is separated from other cannabinoids found in hemp and cannabis. Previously, users and researchers believed that CBD isolates were more potent than full spectrum CBD hemp edibles. But that myth was eventually proven wrong by different studies performed in recent years. Therefore, full spectrum CBD oil is more effective than CBD isolate.
From anecdotal evidence in humans and from animal studies, CBD appears to affect the way we experience pain, inflammation, and anxiety. “Scientists have identified a number of receptors in the nervous system where CBD acts,” says Orrin Devinsky, MD, professor of neurology, neurosurgery, and psychiatry at NYU Langone. “It’s established that CBD has anti-inflammatory properties and can increase activity at some serotonin [the feel-good neurotransmitter] receptors.”
Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, M.D., clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger. This is why Amanda Oliver, 31, a career consultant in Charleston, SC, pops a CBD gummy bear each night before bed. “I used to lie there tossing and turning as my mind raced from work projects to whether I had set the home alarm,” Oliver says. One piece of candy with 15 mg of CBD is enough to shut off her brain and facilitate sleep. She also swears by the CBD oil she takes at the height of her period, which she says quells her debilitating cramps.
CBD is one of over 110 active cannabinoids inside marijuana plants and is most predominant inside the resin glands (trichomes) of the female cannabis plant. Your body contains cell receptors known as cannabinoid receptors. Cannabinoids, found in cannabis, are agonists that bind to these receptors. Cannabinoid receptors can be found all over the body including, but not limited to, the:
Sarah Jorczyk is an advocate for CBD products and one of the Administrators of the CBD Oil Users Group on Facebook. She strives to educate the public, and promotes the use of safe products while helping others throughout their CBD journey. You can also find a variety of her content, including reviews and educational videos, on the group's youtube page.

Disclaimer: The Federal Food, Drug, and Cosmetic Act requires this disclaimer. We collected this information from various sources for the convenience of our customers. The statements made regarding these products were not evaluated by the Food and Drug Administration. The efficacy of these products is not confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure, or prevent any disease. The information presented here is not meant as a substitute for information from health care practitioners. It is also not meant as an alternative to information from health care practitioners. Before using any product, you should consult your doctor and ask about the risk of interactions or complications.
You can also mix this full-spectrum hemp CBD oil into your favorite beverage. Keep the Bluebird Botanicals CBD oil refrigerated, and shake well before use. While most people find their sweet spot at around 15 drops, your serving size may vary according to your metabolism. Since there are no side-effects and there is no danger of overdosing, you can safely tweak your serving size to find the perfect amount of CBD your body needs. Below you’ll find CBD concentration conversions according to Bluebird Botanicals:

Full spectrum CBD also contains a variety of essential vitamins, minerals, fatty acids, protein, chlorophyll, terpenes, flavonoids, and fiber. When referring to CBD in the hemp plant, it’s important to understand that hemp contains a large number of cannabinoids (in trace amounts), but the main compound is cannabidiolic acid (CBDa). As CBDa is more abundant in the hemp plant, firms must decarboxylate the oil. This process heats the oil and changes CBDa into CBD.


Since our beginning, Medical Marijuana, Inc. has been striving to bring the health benefits of cannabinoids to the lives of as many people as possible through cannabinoid hemp oil supplements. With our knowledge of cannabinoids and the endocannabinoid system just scratching the surface of what’s possible, there is plenty of potential to find new uses for the myriad of cannabinoids available to us.
Given CBD’s reputation as a popular, artisanal remedy, one would think that Epidiolex would command a lot of “off label” attention. After all, physicians often prescribe pharmaceuticals off label to treat conditions that were not the actual focus of clinical trials. But the costly price tag for Epidiolex (more than $30,000 annually) precludes off label prescribing as well as affordable access for tens of millions of Americans without health insurance.
This article may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and is subject to the Safe Harbor created by those sections. This material contains statements about expected future events and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements by definition involve risks, uncertainties.
×