CBD has become quite popular over the last couple of years but despite what you might think, it is only one of the 100+ compounds that have been identified in the Cannabis Sativa L plant. Full Spectrum CBD oil, unlike CBD isolate products, includes a wide range of cannabinoids present in the cannabis or hemp plant. Depending on the condition and what you are looking to achieve, it can provide a greater effect than CBD alone as all the cannabinoids work together in what is known as the entourage effect (more on that later).
No one’s really sure: “It’s astonishing that there’s still no real consensus on how CBD works,” says McLaughlin. “One thing we do know is that it doesn’t work through the same receptors as THC, and, in fact, seems to have the opposite effect.” THC mainly binds to a certain type of receptor (known as CB1) in the brain. But with CBD, he says, “there seems to be a lot of complex targets”—which means CBD may affect multiple pathways throughout the body.
While it is clear that full spectrum CBD may be more effective than isolate CBD, even at lower dosages, it may have some drawbacks. Full spectrum vs regular CBD comes down to this drawback for many people. If full spectrum CBD oil is not an option for you due to your obligations or lifestyle, this can help you make your decision more easily for sure.
Recently I asked myself this very question and the more I read the more contradictory statements I found and the more confused I became. With an extensive background in medical marijuana and high THC strains I felt I had a good grasp on which one was “better” before I started researching for this article and could make a good argument for why medical marijuana derived CBD is better than hemp derived CBD.  More recently I have been introduced to CBD derived from hemp and after some preliminary research I was not so sure. Fortunately, I have connections from within the industry and so my mission began. I set out to talk to the largest names on both sides of the spectrum and get their opinions on this matter.
Basically, cannabis is an umbrella term that includes both hemp and marijuana plants. Cannabis sativa is actually the scientific name of the cannabis plant (Cannabis = genus; sativa = species), and hemp and marijuana are just two different “varieties” of it (i.e. you could refer to both marijuana and hemp plants as “cannabis” plants, but you would not, for instance, refer to a “marijuana” plant as a “hemp” plant). Hopefully that’s not too confusing.
Because the FDA considers CO2 extraction to be GRAS or “generally regarded as safe” for commercial extraction, this method is popular in the food industry. The stability of supercritical CO2 also allows most compounds to be extracted with little damage. In the coffee industry, supercritical CO2 is already widely accepted as safer than traditional solvents to extract the caffeine from decaffeinated coffee beans.
It is for this reason that all the finished hemp goods that you see for sale in America, from food products to clothing to building materials, are part of an imported hemp industry that has surpassed $688 million annually. The size of this import industry is one of the major catalysts for hemp legalization in the U.S. As a renewable source of a range of products, hemp provides an exciting new step in American agriculture.

From anecdotal evidence in humans and from animal studies, CBD appears to affect the way we experience pain, inflammation, and anxiety. “Scientists have identified a number of receptors in the nervous system where CBD acts,” says Orrin Devinsky, MD, professor of neurology, neurosurgery, and psychiatry at NYU Langone. “It’s established that CBD has anti-inflammatory properties and can increase activity at some serotonin [the feel-good neurotransmitter] receptors.”


Quality is a particular concern, because cannabis plants easily soak up heavy metals from pesticides and other contaminants, Marcu says. If you are buying online, look for a company that documents how it tests its products. (If the website doesn’t indicate this, call and ask.) “Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.
*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.
The appeal? Proponents claim CBD can help ease pain, anxiety, depression and stress, boost focus and productivity, improve the immune system, reduce inflammation and more. And – unlike its psychoactive cousin THC – CBD, they say, is harmless, legal and can't get you high. "The known is it's good for you, it helps a lot of people and a lot of things, and you can't hurt yourself," says Phil Asquith, a farmer and producer of extra-virgin olive oil in California, who founded one of the first companies in the CBD space. "The unknown is all the details."

Since it is non-toxic and non-flammable, supercritical CO2 is preferable over chemical solvents like butane, hexane, and acetone, which can linger in the extracted oil if not purged correctly, rendering the oil toxic. It has also been noted that botanical essential oils extracted using supercritical CO2 are truer to the scent of the original plants than in other forms of extraction, meaning more of the plant’s chemical structure is retained in the oil with the use of CO2.
Since our beginning, Medical Marijuana, Inc. has been striving to bring the health benefits of cannabinoids to the lives of as many people as possible through cannabinoid hemp oil supplements. With our knowledge of cannabinoids and the endocannabinoid system just scratching the surface of what’s possible, there is plenty of potential to find new uses for the myriad of cannabinoids available to us.
Full spectrum CBD, like hemp oil, contains every cannabinoid present in the cannabis plant. This means cannabidiol, cannabicyclol, tetrahydrocannabivarin, and cannbichromevinaric acid, to name a few. In full spectrum CBD oil, there is nothing held back or left out. These mixed together compliment each other and produce an entourage effect. This effect is good for the health of the user because the individual is taking all of the properties of all the terpenes and cannabinoid mixed together. All of these combined properties make the user absorbent of more effective effect and treatment. The treatment is very much beneficial for the health of the user hence that is why many users consider the full spectrum CBD far better than Isolate is CBD. Most products of CBD are from full-spectrum CBD.
And without high-quality trials, experts don’t know how much is best for a given purpose. The staff at Roth’s dispensary told her, “Try some once or twice a day and see what happens.” (Half a dropper’s worth was a good amount for her.) One thing scientists feel confident about is that CBD is not dangerous. It won’t damage vital organs even at doses as high as 5,000 mg a day, Marcu says, and nobody has died from simply overdosing on a cannabis product.
Full spectrum (or “whole plant”) products contain CBD as well as terpenes and other cannabinoids such as CBG, CBN and trace amounts of THC. Usually these will be in ratios that were naturally-occurring and extracted from the plant and specific strain. Terpenes and cannabinoids are occasionally added back into products as an isolated form to raise the potency of the product.
CBD and THC interact with our bodies in a variety of ways. One of the main ways they impact us is by mimicking and augmenting the effects of the compounds in our bodies called “endogenous cannabinoids” - so named because of their similarity to the compounds found in the cannabis plant. These “endocannabinoids” are part of a regulatory system called the “endocannabinoid system”.
I think the full spectrum oils are better for medicinal usage. I am suffering from ulcerative colitis, there were more relapses earlier, but I started taking the Purekana CBD oil and now I feel better. Able to stay healthy for longer durations, the vomitings are less severe even during the episode. I had tried some isolates earlier, as my doc is also a kind of genius who keeps on doing his own research, but the full spectrum worked better for my disease. Probably it would go away some day. I am 34 year female and I just weigh 46 Kg at a 5 ft 6inch height!

It probably depends on each individual’s preference, but many researchers support the effects of the full spectrum CBD. They say that the full spectrum’s healing factors through the “entourage effect” are very useful for the treatment of any of the chronic condition. This is why the full spectrum CBD has to be part of the ingredients, not the isolate non-pure one.
The cannabidiol oil is derived from flowers of cannabis plants and is concentrated in its resin glands or trichomes. These glands contain oil that is rich in CBD which differs in quality and quantity between different strains of the cannabis plant. The active CBD available in the flower can be purified and concentrated using precise production techniques. When oil of high potency and concentration is derived from the glands then it can be used in lesser dosage. This lesser dosage saves money as CBD oil is an expensive product but produces the desired effect.
Given CBD’s reputation as a popular, artisanal remedy, one would think that Epidiolex would command a lot of “off label” attention. After all, physicians often prescribe pharmaceuticals off label to treat conditions that were not the actual focus of clinical trials. But the costly price tag for Epidiolex (more than $30,000 annually) precludes off label prescribing as well as affordable access for tens of millions of Americans without health insurance.
Unfortunately, you don’t. Even though more than half of all U.S. states now allow marijuana for medicinal purposes—and nine of those, plus Washington DC, allow it for recreational use—the Drug Enforcement Agency still views CBD as a banned substance and therefore doesn’t regulate it (since, in the eyes of the law, CBD shouldn’t be on the market). “I can start a company, put oil in a jar and sell it as CBD oil,” says McLaughlin—and no one has to vouch that what’s in there is for real. You have only the manufacturers word for it.
When extracting a pure botanical oil from hemp, a solvent is passed through the plant material, pulling the compound rich oil from the plant. The solvent is then removed in a purging process, leaving behind a concentrated oil. When extracting from hemp, the oil can next be formulated into finished products or further refined and purified into a number of forms, including a golden dewaxed concentrate or crystallized CBD isolate.

Lisa Hamilton, a jeweler and doula in Brooklyn, NY, knows about the side effects. She recently tried CBD for the shoulder pain that plagued her five years after an accident. Her doctor certified that she was in chronic pain, which under New York State law allowed her to buy from a state dispensary. One Friday, she swallowed two 10-mg capsules, the amount recommended at the dispensary, then took another two on Saturday. “By Sunday, it felt like I’d gotten hit by a truck. Every muscle and joint ached,” Hamilton says. She cut back to one pill a day the following week, but still felt hungover. She stopped after that.
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