Since it is non-toxic and non-flammable, supercritical CO2 is preferable over chemical solvents like butane, hexane, and acetone, which can linger in the extracted oil if not purged correctly, rendering the oil toxic. It has also been noted that botanical essential oils extracted using supercritical CO2 are truer to the scent of the original plants than in other forms of extraction, meaning more of the plant’s chemical structure is retained in the oil with the use of CO2.
So, many of CBD's popularized benefits aren't well-proven. But are there any harms in trying CBD-containing products? In a word, yes. While any reported side effects from CBD alone are minor (think dry mouth and dizziness), they can be serious if the CBD products interact with other medications, experts say. Since CBD is metabolized by the same enzyme in the liver that metabolizes many conventional medicines and supplements, the chemical can cause the levels of other drugs in the system to rise; in some cases – like for those taking a drug to prevent their bodies from rejecting a donor organ – to a deadly level, Tishler says.
Because the FDA considers CO2 extraction to be GRAS or “generally regarded as safe” for commercial extraction, this method is popular in the food industry. The stability of supercritical CO2 also allows most compounds to be extracted with little damage. In the coffee industry, supercritical CO2 is already widely accepted as safer than traditional solvents to extract the caffeine from decaffeinated coffee beans.
Along with its better-known counterpart, THC (delta-9-tetrahydrocannabinol, the chemical that produces the marijuana high), CBD is one of more than 400 compounds found in the oils of cannabis plant species, which include marijuana and hemp. Unlike THC, CBD will not make you high. That said, this doesn’t mean CBD is not at all psychoactive, as many assert, says Jahan Marcu, Ph.D., director of experimental pharmacology and behavior at the International Research Center on Cannabis and Mental Health in New York City: “CBD does change cognition. It affects mood, which is why people take it for anxiety. And some find that it makes them more alert.”
In other words, many popular claims remain unfounded – and overlook the fact that there's a difference between CBD that's studied in labs for particular conditions and CBD products that are sold to consumers for general well-being. "What happens is people say, 'Look, CBD is harmless and it doesn't get me intoxicated, so I'm going to take it for what ails me," says Dr. Jordan Tishler, a Harvard physician and CEO of InhaleMD, a Boston-area practice specializing in cannabis therapeutics. "Then they're going to get some perceived benefit because that's the way the placebo effect works, and then they go and trumpet this."
Because the FDA considers CO2 extraction to be GRAS or “generally regarded as safe” for commercial extraction, this method is popular in the food industry. The stability of supercritical CO2 also allows most compounds to be extracted with little damage. In the coffee industry, supercritical CO2 is already widely accepted as safer than traditional solvents to extract the caffeine from decaffeinated coffee beans.
With the rapid rise in the popularity of CBD in everything from vape juice to lattes, many people are asking- “what is CBD oil?”. To answer that question, let’s first answer the question- what is CBD? CBD, short for cannabidiol, is a compound found in hemp plants. CBD’s benefits are numerous, making it a popular supplement. We’ll explore the effects of CBD oil in more depth below, but in short, it interacts with receptors that keep the body balanced and running normally.
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