Unlike THC, which primarily binds to CB-1 receptors located in the brain, CBD works in the body by manipulating receptors throughout organ tissues, the immune system, the pain response system, the hormonal system, and other whole-body regulatory systems. Basically, since its receptors have been found to exist in virtually every cell and tissue type in the body, CBD is believed to work on every aspect of human health and behavior – from the subcellular level to the whole-body leve and beyond.

My Wife had Polio at age 5 and the lingering damage to the L leg and muscle drove her crazy. At age 21 she was using heavy doses of muscle relaxers and pain meds. Needed to bomb herself at night to get some sleep. A Post polio group in West Palm Beach told her about Marijuana and she got some from the Jamaican health aide that was her constant helper. After 5 months she quit all meds. All of them. Slowly came out of the drugged state the meds had caused from 15 years of use. We separated good friends and I know she has gone back to school and getting a degree. All from the help of a plant from Jamaica. I never understood the statement this plant has no viable medical value. Something smells in the politics of this prohibition. Shame.


Another concern is about medications with which CBD might interact. This won’t be an issue with most drugs, says Sunil Kumar Aggarwal, M.D., Ph.D., a palliative medicine physician and scientist who studies cannabis and integrates it into his Seattle medical practice. The exceptions are blood thinners, IV antibiotics, and other drugs whose exact dosing is crucial and must be monitored closely, he says. (Of course, if you have a health problem, talk to your doctor before using CBD, and never take it instead of seeing your physician for a serious condition.)
Physical Wellness is the ability to maintain a healthy quality of life that allows us to get through our daily activities without undue fatigue or physical stress. The ability to recognize that our behaviors have a significant impact on our wellness and adopting healthful habits (routine check ups, a balanced diet, exercise, etc.) while avoiding destructive habits (tobacco, drugs, alcohol, etc.) will lead to optimal Physical Wellness.
Hemp Bombs is a brand that has been on the market for a good amount of time. The brand used to source its hemp from Europe but has switched to the United States. The brand’s website explains that the brand is working to ensure that the products are made in a sustainable manner. A few of the product options include topicals, vape liquids, gummies, and tinctures.
Cannabis sativa L. subsp. sativa var. sativa is the variety grown for industrial use in Europe, Canada, and elsewhere, while C. sativa subsp. indica generally has poor fiber quality and is primarily used for production of recreational and medicinal drugs. The major difference between the two types of plants is the appearance and the amount of THC secreted in a resinous mixture by epidermal hairs called glandular trichomes. Strains of Cannabis approved for industrial hemp production produce only minute amounts of this psychoactive drug, not enough for any physical or psychological effects. Typically, Hemp contains below 0.3% THC, while Cannabis grown for marijuana can contain anywhere from 6 or 7 % to 20% or even more.
In the Australian states of Tasmania, Victoria, Queensland, New South Wales, and most recently, South Australia, the state governments have issued licences to grow hemp for industrial use. The first to initiate modern research into the potential of cannabis was the state of Tasmania, which pioneered the licensing of hemp during the early 1990s. The state of Victoria was an early adopter in 1998, and has reissued the regulation in 2008.[77]

It’s still very early in the days of cannabis research but there is a strong case for the therapeutic benefit of a less refined full spectrum hemp extract with more of the plant compounds intact. There are so many beneficial health possibilities waiting to be unlocked by further studying the combinations of these compounds found in hemp and cannabis.
3. Reduce Stress-This step is usually easier said than done. Reducing stress is a key element of our overall wellness. Stress affects many parts of our bodies and minds in a negative way. Some everyday ways to reduce stress is to take a moment to breathe deeply, relax your muscles from head to toe, take up yoga or tai chi, meditate or even splurge on a massage. Find what works best for you. At work get organized, declutter your desk, make lists of what you must accomplish and learn to say “no” sometimes. Your overall wellness will thank you.
Maintaining an optimal level of wellness is absolutely crucial to live a higher quality life. Wellness matters. Wellness matters because everything we do and every emotion we feel relates to our well-being. In turn, our well-being directly affects our actions and emotions. It’s an ongoing circle. Therefore, it is important for everyone to achieve optimal wellness in order to subdue stress, reduce the risk of illness and ensure positive interactions.
The etymology is uncertain but there appears to be no common Proto-Indo-European source for the various forms of the word; the Greek term kánnabis is the oldest attested form, which may have been borrowed from an earlier Scythian or Thracian word.[10][11] Then it appears to have been borrowed into Latin, and separately into Slavic and from there into Baltic, Finnish, and Germanic languages.[12] Following Grimm's law, the "k" would have changed to "h" with the first Germanic sound shift,[10][13] after which it may have been adapted into the Old English form, hænep. However, this theory assumes that hemp was not widely spread among different societies until after it was already being used as a psychoactive drug, which Adams and Mallory (1997) believe to be unlikely based on archaeological evidence.[10] Barber (1991) however, argued that the spread of the name "kannabis" was due to its historically more recent drug use, starting from the south, around Iran, whereas non-THC varieties of hemp are older and prehistoric.[12] Another possible source of origin is Assyrian qunnabu, which was the name for a source of oil, fiber, and medicine in the 1st millennium BC.[12]
All of the product reviews listed on this website are real reviews from real users. Recommended brands are selected solely based on merit. Our vetting process includes analysis of product quality based on third party lab reports, customer service quality and responsiveness, industry reputation, company longevity and customer feedback. Per FTC guidelines, we do participate in the affiliate programs of some but not all of the recommended brands whereby we receive a small commission on purchases made through links on this website. Any references to third party products, prices or websites referenced in this group are subject to change without notice.
The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide far better performance than any single compound alone, and that includes CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
One claim is that Hearst believed[dubious – discuss] that his extensive timber holdings were threatened by the invention of the decorticator which he feared would allow hemp to become a cheap substitute for the paper pulp used for newspaper.[125][128] Historical research indicates this fear was unfounded because improvements of the decorticators in the 1930s – machines that separated the fibers from the hemp stem – could not make hemp fiber a cheaper substitute for fibers from other sources. Further, decorticators did not perform satisfactorily in commercial production.[129][125]
@martha – I just started taking an organic full spectrum oil (from a highly reputable and recommended company) for the last two weeks and decided to take an at-home THC urine test for the same concerns you have and I tested positive. I’m now a little nervous since my employer facilitates random drug screenings frequently. Here’s an article with more details: https://www.marijuanabreak.com/failed-drug-test-after-taking-cbd-oil/amp
CBD has most of these qualities thanks to its ability to act on serotonin receptors in our brains. Serotonin is a neurotransmitter that maintains our mood. It is responsible for how our body regulates social behavior.Cannabis is something that doctors tend to rule out for people with chronic anxiety. That’s because THC can easilygger anxiousness and paranoia. Unlike THC, CBD can actually help reduce the levels of anxiety in people who suffer from conditions such as panic disorder, social anxiety disorder, OCD and similar.

And in the medical world, we've really just barely begun to scratch the surface of the many potential uses of CBD as an alternative, plant-based form of medicine. From the FDA approving a revolutionary CBD-based drug used to treat epilepsy, to studies proving that cannabis has helped patients with glaucoma and those suffering from inflammation, one point is becoming increasingly clear: CBD can help people with all sorts of ailments.


Hemp has been grown for millennia in Asia and the Middle East for its fibre. Commercial production of hemp in the West took off in the eighteenth century, but was grown in the sixteenth century in eastern England.[148] Because of colonial and naval expansion of the era, economies needed large quantities of hemp for rope and oakum. In the early 1940s, world production of hemp fiber ranged from 250 000 to 350 000 metric tonnes, Russia was the biggest producer.[129]
VerifiedCBD.com: VerifiedCBD strives to keep you totally fulfilled and gratified, which is why we offer a 30-day, money back guarantee. If at any point you decide it’s not the most nutritious, delicious superfood mix on the planet, remember you are protected by the highest standard 100% money-back guarantee. Just send us the empty bottle and we’ll refund you to the last penny, no questions asked. If after 30 days of use, you are unhappy and would like a refund, here’s exactly what to do:
Carol, thanks for your long and detailed post, and the links. In your paragraph where you reference various effects, you write “cannabis” several times. There are several components of “cannabis”, THC is the more psychoactive component – and current varieties have been bred/engineered to have ever increasing concentrations of this. CBD is another component, which has different and in some cases opposing effects vs. THC. Are the statements you made about effects of “cannabis”, do they center on THC, consumption/use of the whole plant, or have they broken out a purified CBD product and tested the impacts of just that component. Earnest question.
While there is much debate on which form is better, this 2015 study leans in favor of full spectrum CBD oil products. There are many that believe that other cannabinoids, THC especially, are necessary to take full advantage of what cannabis has to offer. Ultimately, however, we are all different and it comes down to the individual user and their needs. If drug testing is a concern, you’re encouraged to seek out CBD isolate products (or terpsolates) or broad spectrum products instead of full spectrum.

In recent months, both cities and states have moved to control how CBD is sold. Maine and New York City have moved to crack down on edible products containing CBD. New York’s health department confirmed to the New York Times that it has started ordering restaurants to stop selling CBD-laced food because it has not been “deemed safe as a food additive.”


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CatryNA49; Cannabis, like Opium poppies, and the substances derived from these plants, were also made illegal as a means of preventing white females, from being seduced, and or raped by male members of minority races; seriously ! In the early 70s Nixon administration officials oversaw the expansion of drug laws, as a means of legally repressing the two groups of Americans, that administration deemed to be their biggest foes; those groups being, African Americans, and the antiwar left. We know the drug war, just like the earlier less repressive drug laws, was initiated as a means of legal political, and racial repression because of the fact that a Nixon adm. official is on film, admitting as much. You can Google that film if you like. Now despite the truth about the drug war being admitted on film, for anyone in the world who has internet access can see, the drug war continues to be waged by politicians; the same politicians by the way, that tens of millions of Americans continue to vote for. I should add, that in the last presidential election, the candidate who promised to refuel the drug war, was the candidate who won that election. Of course what else could you expect, being that we live in the land of the free and the home of the brave ?!
Industrial Hemp is produced in many countries around the world. Major producers include Canada, France, and China. While more hemp is exported to the United States than to any other country, the United States Government does not consistently distinguish between marijuana and the non-psychoactive Cannabis used for industrial and commercial purposes.
The CBD-product industry has flourished in the past few years and now, we’re headed into 2019 and it seems like the ideal time to reflect on the products on the market. This is especially true in light of the fact that there is an overwhelming amount of research showing all of the good that the products bring to men and women who suffer from various health issues, conditions, and who want to experience an improvement in their wellness.

Sativex, an oral spray containing both CBD and THC, can treat MS-induced pain. During one study, researchers gave Sativex to 47 participants with MS. Results were largely positive. Patients who used this spray felt notably better. Their muscle and walking spasms decreased, and they felt pain relief. Thanks to studies such as this one, several countries approved using Sativex in MS treatment.
Ehler Danlos has recently been found to be caused by hereditary alpha tryptasemia with mast cell activation. You are born with extra copies of the alpha tryptase gene. Tryptase levels can be lowered by lactoferrin found in the supplement colostrum. Also, supplement with luteolin which inactivates mast cells. The cells of connective tissue include fibroblasts, adipocytes, macrophages, mast cells and leucocytes. Histamine activates mast cells increasing inflammation which attacks connective tissue, so eat an anti-histamine diet which lowers inflammation. To lower histamine levels, eat only fresh foods- eggs, chicken, rice, gluten free pasta/crackers, cream cheese, butter, coconut oil, olive oil, non-citrus juices, milk, herbal teas (not coffee, black tea), fresh/frozen fish, fresh/frozen fruits and vegetables, especially prebiotics like onions, garlic, bananas, jicama, raw asparagus. No tomatoes, strawberries, vinegar, matured cheeses, pickled/canned foods, shellfish, salami and other cured meats, sausages, ham, bologna, etc. No beans, nuts chocolate, peanut butter, ready meals, deli food because its been sitting, energy drinks, as these are all high in histamines. The key to low histamine is fresh. Eat knox gelatin daily with vitamin C which strengthens connective tissue. Gelatin is high in the amino acids- glycine, proline and lysine which are needed for collagen production in connective tissue. No aspirin, alcohol, high sugar, fructose, or high carbs to heal leaky gut. In fact, inflammation throughout the body can be mediated by the gut bacteria, and loss of gut bacterial diversity can threaten the gut lining, so then that leakiness of the gut, or intestinal permeability, then mechanistically leads to inflammation. Bacteria from the gut leaks into the bloodstream causing inflammation. Then where does that inflammation go and what part of the body gets damaged from it? Connective tissue. Inflammation is the cornerstone of basically every degenerative condition you don’t want to get. Check your progesterone levels which should be normalized. Progesterone’s role in the health of the body’s connective tissue or collagen is well understood. As progesterone strengthens collagen and increases the turnover of cells, the skin becomes softer and stronger. 70% of the skin is collagen, as is 20% of the entire body- tendon, ligament, blood vessels, skin, cornea, cartilage, bone, blood, blood vessels, gut, intervertebral disc, brown and white adipose tissue. https://www.niaid.nih.gov/research/hereditary-alpha-tryptasemia-faq
Who said pets can't get in on the CBD oil craze, too? Not us! This line of CBD oil from Austin, Texas-based brand Grassroots Harvest is engineered specifically with pets in mind. Using high-quality full-spectrum CBD mixed with salmon oil to appeal to our fuzzy friends' taste buds, this CBD oil is great for pets who suffer from separation anxiety, inflammation in tender areas like the hips or joints, seizures, and a whole list of other ailments.
I always quote CBD oil as a “miracle cure”. The reason being when no other regular meds helped me there was CBD oil that helped me with my chronic back pain. Been using it for the past 2 years now. I haven’t tried the Kope CBD products but after reading this I’m curious. Rest all brands are well known to me. Let’s give Kope a try. Anyways, thanks for sharing this awesome information.
The important thing is that you have to be SUPER careful when selecting CBD oils. Since the cannabis industry is not FDA-regulated, there have been dozens and dozens of companies trying to get away with selling very low quality (and even potentially toxic), “snake oils” that have been extracted using harsh chemical solvents like butane and hexane. Make sure you stay away from cheap products like these, as they could damage your health.
CBD (short for cannabidiol) is one of at least 113 chemical compounds known as cannabinoids that are found in the cannabis plant. The popularity of CBD oil products continues to increase as more consumers learn about the potential health benefits. Anxiety, depression, chronic pain, inflammation and insomnia are just a few of the conditions cited by users who are successfully using CBD oil products.
In the United Kingdom, cultivation licences are issued by the Home Office under the Misuse of Drugs Act 1971. When grown for nondrug purposes, hemp is referred to as industrial hemp, and a common product is fibre for use in a wide variety of products, as well as the seed for nutritional aspects and for the oil. Feral hemp or ditch weed is usually a naturalized fibre or oilseed strain of Cannabis that has escaped from cultivation and is self-seeding.[93]
In short, the results of the survey (which were published in the Journal of Pain Research) showed that roughly 42% and 46% (respectively) of participants claimed they were able to use cannabis in place of traditional medical to effectively treat their specific medical ailment. So if you’re wondering how to know if you need CBD for pain, remember that you’re certainly not alone.
Regarding your comment on CBD and colitis or inflammatory bowel disease. Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat do not sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues. When the balance tilts too far toward inflammation, inflammatory bowel disease can result. Now, researchers have found that a kind of tolerance-promoting immune cell appears that carry a specific bacterium in guts called Lactobacillus reuteri that is the normal part of the gut microbiome, and tryptophan, part of a protein-rich diet, soothes the inflamed gut because it increases the development of a population of immune cells that promote tolerance. Further, the bacterium needs tryptophan — one of the building blocks of proteins — to trigger the cells’ appearance, and the more tryptophan in the diet to feed the gut bacterium, Lactobacillus reuteri, the more of these immune cells there are.
Cohen has found that chronic conditions including autoimmune diseases and pain syndromes can be helped with a 6-mg under-the-tongue tincture (the fastest delivery system) or a 25-mg capsule taken twice a day. Dosages for topical products like lotions are especially hard to determine—there’s no clarity on how much CBD gets into the system through the skin.
Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.

However, CBD edibles also come in other forms, acceptable for non-human use. For example, CBD for dogs and CBD for cats has become a widespread way of providing our furry friends with comfort and pain relief. We can give CBD oil for dogs to our canine friends in the form of CBD dog treats. Furthermore, CBD oil for cats comes in a similar form, and we can use it to treat various diseases and conditions, like the Alzheimer’s, Parkinson’s, and Crohn’s disease, but also for treatment of pain, anxiety, nausea, cancer, and any inflammatory diseases.

The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice.


The seeds are sown with grain drills or other conventional seeding equipment to a depth of 1.27 to 2.54 cm. Greater seeding depths result in increased weed competition. Nitrogen should not be placed with the seed, but phosphate may be tolerated. The soil should have available 89 to 135 kg/ha of nitrogen, 46 kg/ha phosphorus, 67 kg/ha potassium, and 17 kg/ha sulfur. Organic fertilizers such as manure are one of the best methods of weed control.[60]
There has been a dramatic rise in news attention to medicinal cannabis in 2013, with reports on CNN, ABC, CBS, and local publications about high-cannabidiol cannabis oil effectively controlling the symptoms of rare epileptic conditions like Dravet syndrome, Doose syndrome, infantile spasms, cortical dysplasia, and more. These diseases can cause hundreds to thousands of seizures a week, while also impairing development in a number of other ways. For families with children suffering from such conditions, the challenges are overwhelming.
I am confused about how you say it can be beneficial for cancer and has anti-tumor effects, but then in the side effects, you say that since it can lower T and B cell activity it can worsen disease progression, tumor growth and mestastases. My mom has early stage multiple myeloma as well as some anxiety/depression and insomnia. Thought this would be good- but now confused whether it’s anti or pro cancer.
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