I think the full spectrum oils are better for medicinal usage. I am suffering from ulcerative colitis, there were more relapses earlier, but I started taking the Purekana CBD oil and now I feel better. Able to stay healthy for longer durations, the vomitings are less severe even during the episode. I had tried some isolates earlier, as my doc is also a kind of genius who keeps on doing his own research, but the full spectrum worked better for my disease. Probably it would go away some day. I am 34 year female and I just weigh 46 Kg at a 5 ft 6inch height!