Instead, the human body manages cannabinoids through its endocannabinoid system, also known as ECS, which can process CBD and hemp oil through the body and is managed by the human brain, which uses cannabinoids to regulate the body's physiological reactions to the herb, and help better manage key human elements like eating, sleeping, dealing with pains and illnesses, and improving mood.
Given CBD’s reputation as a popular, artisanal remedy, one would think that Epidiolex would command a lot of “off label” attention. After all, physicians often prescribe pharmaceuticals off label to treat conditions that were not the actual focus of clinical trials. But the costly price tag for Epidiolex (more than $30,000 annually) precludes off label prescribing as well as affordable access for tens of millions of Americans without health insurance.
The health benefits of full-spectrum hemp go beyond it being a source of CBD. The array of cannabinoids and other natural constituents found in full-spectrum hemp oil work have been shown in studies to work together in what’s referred to as the “entourage effect.” Together, these compounds work harmoniously to magnify their therapeutic properties. The complex mix of cannabinoids, essential nutrients, protein, and healthy fats work synergistically to encourage homeostasis and balance in our health.
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No one’s really sure: “It’s astonishing that there’s still no real consensus on how CBD works,” says McLaughlin. “One thing we do know is that it doesn’t work through the same receptors as THC, and, in fact, seems to have the opposite effect.” THC mainly binds to a certain type of receptor (known as CB1) in the brain. But with CBD, he says, “there seems to be a lot of complex targets”—which means CBD may affect multiple pathways throughout the body.
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Recently I asked myself this very question and the more I read the more contradictory statements I found and the more confused I became. With an extensive background in medical marijuana and high THC strains I felt I had a good grasp on which one was “better” before I started researching for this article and could make a good argument for why medical marijuana derived CBD is better than hemp derived CBD. More recently I have been introduced to CBD derived from hemp and after some preliminary research I was not so sure. Fortunately, I have connections from within the industry and so my mission began. I set out to talk to the largest names on both sides of the spectrum and get their opinions on this matter.
CBD hemp oil is the product derived from the hemp plant, which is high in CBD (cannabidiol) and low in THC (tetrahydrocannabinol). This oil has received a large amount of attention in recent years, due to the growing wave of marijuana legislation and debate in many countries, including the United States. While cannabis and smoking marijuana (which often has a high level of the psychotropic compound THC) is still illegal in many places, as more is being learned about CBD, and its potential effects on health, it is becoming more and more accepted as a legal and safe remedy for a wide variety of health conditions. Since it has a minimal amount of the psychotropic compound THC, use of this oil does not result in a traditional “high”, so its effects are generally considered therapeutic, not mind-altering.
That leaves those touting CBD’s effectiveness pointing primarily to research in mice and petri dishes. There, CBD (sometimes combined with small amounts of THC) has shown promise for helping pain, neurological conditions like anxiety and PTSD, and the immune system—and therefore potentially arthritis, diabetes, multiple sclerosis, cancer, and more.
Just one last thing before we explain the benefits of full spectrum CBD oil; it’s important to understand that CBD from cannabis is only legal in medical or recreational states, while CBD hemp oil is legal in all 50 states under the 2014 US Farm Bill. While it may not be able to treat all conditions, it has been known to assist with a variety of medical conditions including anxiety, depression and acute pain.
“What is CBD oil” may be your first question, but the real question we have to answer is, “What does CBD oil do?” CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. Like an acrobat on a highwire, as the environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to keep us level.