Dr. Devinsky’s research, which was recently published in The New England Journal of Medicine, is beginning to provide that much-needed data in the field of epilepsy research. In a landmark multinational randomized double-blind study for a treatment-resistant form of the condition, subjects taking an oral solution of 20 mg CBD per kilogram of body weight for 14 weeks, along with standard treatment, experienced a 42 percent reduction in drop seizures (the muscles go limp). Those taking a 10 mg CBD per kilogram of body weight saw a 37 percent decrease; patients who got a placebo saw a 17.2 percent decrease. The mechanism hasn’t quite been worked out yet, Dr. Devinsky says, though there’s some evidence that a receptor known as GPR55 may be critical for the anti-seizure effect.
Industrial production of CBD oil is done by combining the cannabinoid rich plant with other compounds like CO², butane, ethanol or olive oil etc., all of which leave their residues in the final product. The most important part of CBD oil extraction is selection of right plant for the extraction of oil. Cost of final product will depend on its potency and purity which is controllable only via oil extraction technique.
There is a strong sedative quality to CBD hemp oil, making it a popular remedy for people with insomnia, sleeplessness, interrupted sleep, post-traumatic stress disorder, restless leg disorder, and other night-time issues. Dr. Scott Shannon, Assistant Clinical Professor of Psychiatry at the University of Colorado School of Medicine, USA, published a report in the Permanete Journal, in which he recommended either inhaling a small amount of CBD oil, applying it to one’s chest, or even putting a few drops on one’s pillow to help get a good night’s sleep.
From anecdotal evidence in humans and from animal studies, CBD appears to affect the way we experience pain, inflammation, and anxiety. “Scientists have identified a number of receptors in the nervous system where CBD acts,” says Orrin Devinsky, MD, professor of neurology, neurosurgery, and psychiatry at NYU Langone. “It’s established that CBD has anti-inflammatory properties and can increase activity at some serotonin [the feel-good neurotransmitter] receptors.”
CBD oil is most readily available as a tincture. This can be taken by applying a few drops under your tongue, holding in your mouth for a few moments so it can be absorbed, before swallowing. It can also be added to water or smoothies. A spray form is available (simply spritz under your tongue), as are capsules, gummies, creams that can be applied topically, and e-liquid for vape pens.
Each bottle of Bluebird Botanicals CBD oil comes with a precise dropper, making it easy to measure your exact serving size and adjust it according to your body’s needs. This also allows you to easily combine the CBD oil with any other CBD product to introduce more variety and enrich your daily CBD experience. You can try the Classic Hemp oil alongside any CBD edible or right before your CBD vape for a synergistic effect.
Just one last thing before we explain the benefits of full spectrum CBD oil; it’s important to understand that CBD from cannabis is only legal in medical or recreational states, while CBD hemp oil is legal in all 50 states under the 2014 US Farm Bill. While it may not be able to treat all conditions, it has been known to assist with a variety of medical conditions including anxiety, depression and acute pain.
In the United States marijuana is still listed under Schedule I of the Controlled Substances Act. However, the federal Food and Drug Administration (FDA) has authorized clinical trials on a CBD-based drug that treats childhood-onset epilepsy. CBD oil also shows promise in treating intestinal conditions as well as anxiety, post-workout aches, inflammation, and some types of cancers. Additional conditions are neurological inflammation, oxidative injury, and schizophrenia.
Cutting-edge science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. Thus, it stands to reason that “modulating endocannabinoid system activity may have therapeutic potential in almost all diseases affecting humans,” as Pal Pacher and George Kunos, scientists with the U.S. National Institutes of Health (NIH), suggested in a 2014 publication.
“Marijuana and industrial hemp are different varieties of the same plant species, Cannabis sativa L. Marijuana typically contains 3 to 15 percent THC on a dry-weight basis, while industrial hemp contains less than 1 percent (Blade, 1998; Vantreese, 1998). Most developed countries that permit hemp cultivation require use of varieties with less than 0.3 percent THC. However, the two varieties are indistinguishable by appearance. DeMeijer et al. (1992), in a study of 97 Cannabis strains, concluded that short of chemical analysis of the THC content, there was no way to distinguish between marijuana and hemp varieties.” http://www.ers.usda.gov/media/328202/ages001eb_1_.pdf
While cannabidiol (CBD) is all the rage at present, it is often hard to understand what you are getting. Furthermore, with so many different CBD products on the market, it’s hard to tell which are full spectrum, which are not and which products are made from CBD cannabis or CBD hemp. In this article we will try to clear up any confusion, focusing the major part of the post around Full Spectrum CBD oil.
CBD has become quite popular over the last couple of years but despite what you might think, it is only one of the 100+ compounds that have been identified in the Cannabis Sativa L plant. Full Spectrum CBD oil, unlike CBD isolate products, includes a wide range of cannabinoids present in the cannabis or hemp plant. Depending on the condition and what you are looking to achieve, it can provide a greater effect than CBD alone as all the cannabinoids work together in what is known as the entourage effect (more on that later).
Yes: CBD extracts can’t always be trusted. A 2017 JAMA paper reported that almost 70 percent of all CBD products sold online do not contain the amount of CBD stated on the label. Of the 84 products bought from 31 different companies, 42 percent contained a higher concentration of CBD oil than the label claimed, and 26 percent of the products contained less than the label claimed. The remainder of products contained the labeled amount—give or take 10 percent.
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