Cannabidiol (CBD) is a naturally-occurring compound found in cannabis. It’s known for therapeutic properties and has no psychoactive effects. CBD oil is typically extracted from cannabis plants using either CO2 or ethanol extraction methods. It’s then incorporated into common CBD oil products, including tinctures (drops), vape liquids, gummies, capsules and topical creams and lotions. CBD oil derived from hemp has less than 0.3% THC so is federally legal in the U.S. and can be purchased online or in some local stores. CBD oil derived from marijuana has more than 0.3% THC so can only be purchased at licensed dispensaries in states where medical marijuana is legal.
I have just started on my CBD journey. This is day 3. My knees do not hurt and I am definitely able to tell the difference when things were off. The nights are pain-free. I have a job that I spend a lot of time on my feet, and easily do over 14000 steps just for my job. My feet use to hurt so bad by the end of the night, that I actually would cry on the drive home. This allows me to have much less pain, and an easier time falling and staying asleep.
According to the results of a study published in Neuropharmacology, CBD oil can help reduce the risk of developing diabetes. The research sought to find out the effect of CBD on non-obese, diabetes-prone females mice. Only 32% of the mice administered with CBD contracted diabetes in comparison to 100% of the group that didn’t receive a CBD injection.
As the CBD oil market continues to grow, more and more products are being sold online or in your local health food stores. You can find many types of CBD and each one is used in a different way. The most common forms of CBD available include the following. (Of course, you should always consult your healthcare professional prior to using CBD and read and follow all label directions.)
Hemp’s potential widespread adoption as food for humans is also very promising. Hemp seed has high levels of protein, carbohydrates, fiber, vitamins, essential fatty acids and trace elements. Oil from hempseed, which can comprise nearly a third of the seed’s weight, makes it an ideal source for cooking oil, lighting and biofuels. Hempseed oil is also valuable as a component of personal care products such as soaps, conditioners and lotions.
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Where marijuana can contain up to 30% THC, hemp typically contains only 0.3% or less THC. Hemp is naturally abundant in CBD, however, there is a difference between industrial hemp cultivated for commercial products and industrial hemp cultivated for CBD. Hemp that’s used for mainstream production wasn’t cultivated specifically for high levels of CBD.
Although it may be better to consume CBD alone than nothing at all, it may not offer you the same range of positive effects as full spectrum CBD oil. With full spectrum CBD, not only will you get adequate CBD, but you’ll also consume dozens of beneficial cannabinoids and terpenes. As a result, your body will receive more than enough vitamins, minerals, and nutrients.
People who experience psychosis may produce too much or even too little cannabinoids (from overactive dopamine receptors). CBD is milder than our internal cannabinoids and helps to re-establish a balance of cannabinoids in the brain. CBD also helps lower inflammation, which is often increased in schizophrenia. THC, on the other hand, is stronger than our internal cannabinoids (anandamide and 2-AG), this way potentially triggering psychosis [R+, R].
Just a quick word to say I had a stroke in Feb 2015 so after smoking a joint someone gave I noticed my arm felt like it moved so after doing searches online to find out what it was an yes it was the dope so more looking at bits online I came across CBd oil found where to buy it an thought I will give it a go now I still suffer from lack of movement on one side of my body but my fingers move on demand so hey I’m over the moon to see something that looks like I’m going to make a recovery an maybe get back to living my life yip yip yipee
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, M.D., clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger. This is why Amanda Oliver, 31, a career consultant in Charleston, SC, pops a CBD gummy bear each night before bed. “I used to lie there tossing and turning as my mind raced from work projects to whether I had set the home alarm,” Oliver says. One piece of candy with 15 mg of CBD is enough to shut off her brain and facilitate sleep. She also swears by the CBD oil she takes at the height of her period, which she says quells her debilitating cramps.
In the 2010’s the public began to see what a profound effect CBD oil could have treating a variety of life threatening aliments, especially in children. A prime example of this is a young family from Missoula Montana, using CBD oil to treat their 20 month old son, Cash Hyde, who had been diagnosed with brain cancer in 2010. Hyde’s condition was worsening and his tumor inoperable. After exhausting every treatment option, including 30 rounds of intensive radiation, Ketamine, Methadone and Morphine treatments, the Hyde family had hit their limit. Nothing had worked. In an effort to give his small child some relief, his father did what was thought to be “crazy”at the time, and gave him a highly concentrated cannabis extract, not knowing what else to do. After the first treatment, Hyde’s State IV brain tumor had shrunk. Although it was considered unorthodox, Mike Hyde was applauded by medical professionals and even spoke with the press in hopes of shedding the light on how CBD oil is literally a lifesaver. Cash Hyde lived for another two and a half years, passing away after the State of Montana made a change in legislation that impaired the family from easily accessing the cannabis oil their son needed.
In this review, the effects of cannabinoids in the regulation of the following endocrine systems are discussed: the hypothalamic-pituitary-gonadal axis and hypothalamic-pituitary-adrenal cortex axis. Cannabis users have reduced levels of gonadotropins, reduced prolactin and growth hormone. Cannabis affects corticotropin-releasing hormone-, thyrotropin-releasing hormone-, vasopressin-, and oxytocin-expressing neurons. Therefore, our findings reveal a mechanism of rapid glucocorticoid feedback inhibition of hypothalamic hormone secretion via endocannabinoid release in the paraventricular nucleus of the hypothalamus and provide a link between the actions of glucocorticoids and cannabinoids in the hypothalamus that regulate stress and energy homeostasis. Glucocorticoid negative feedback in the brain controls stress, feeding, and neural-immune interactions by regulating the hypothalamic-pituitary-adrenal axis. Cannabis increases dopamine which decreases prolactin. Cannabis decreases oxytocin, thyroid hormone and growth hormone, and disrupts the hypothalamic-pituitary-adrenal axis. Cannabinoids suppress fertility via reducing hypothalamic gonadotropin- releasing hormone output. γ-Aminobutyric acid (GABA)(A) receptor (GABA(A)-R)-mediated transmission is a major input to gonadotropin releasing hormone cells that can be excitatory. Cannabinoids act via inhibiting GABAergic input. Cannabis disregulates the hypothalamic-pituitary-adrenal axis circadian rhythm. Cannabis decreases serum concentrations of pituitary gonadotropins. Cannabis raises cortisol and ACTH which increases cortisol which uses up progesterone reducing testosterone and estrogen. Cannabis lowers testosterone in men by inhibiting testosterone secretion and impairs fertility in males through alteration in the testicular endocannabinoid system. Cannabis suppresses copulatory behavior even when testosterone levels are maintained. It decreases sperm concentration, causes defective sperm function or alteration of sperm morphology. Endocannabinoids control male reproduction acting at central and local level via cannabinoid receptors. The cannabinoid receptor CB1 has been characterized in the testis, in somatic and germ cells of mammalian and non-mammalian animal models, and its activity related to Leydig cell differentiation, steroidogenesis, spermiogenesis, sperm quality, and maturation. Testicular degeneration and necrosis is induced by chronic administration of cannabis. In both ovulating and menopausal women, cannabis can alter pituitary gonadotropin release and alter metabolism or target tissue response to gonadal steroids, leading to reduced estrogen and progesterone production and anovulatory menstrual cycles. Cannabis presents abnormal longer ovulatory cycle lengths in females. Cannabis suppresses luteinizing hormone when sex hormones are initially high, but, chronic cannabis lowers progesterone and testosterone in men, and lowers estrogen and progesterone in women, so luteinizing hormone significantly increases which raises night time core temperature for disrupted sleep. Cannabis increases hypothalamic nitric oxide which inhibits oxytocin. Cannabis is detrimental for lactating moms. Cannabis decreases maternal care, decreases aggressive instinctual behaviors for protection of young, suppresses maternal anxiolysis, decreases plasma oxytocin levels and milk consumption and decreases activation of oxytocinergic neurons in hypothalamic nuclei. Changes in the behavioral responses of lactating mothers treated with cannabis can be related to disruption in the neuroendocrine control of oxytocin secretion. Cannabis causes impairment of glucocorticoid feedback which either enhances or decreases performance on various tasks. Cannibis can cause a decrease in thyroid which negatively affects cerebellar development and motor performance involved in adult brain function. It induces consistent behavioral changes in adults, leading to severe anxiety and morphological changes in the hippocampus, however, it shows improvements for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side. Cannabis and Δ(9) -THC are anticonvulsant in most animal models but can be proconvulsant in some healthy animals. The simultaneous rapid stimulation of nitric oxide and endocannabinoid synthesis by glucocorticoids has important implications for the impact of stress on the brain as well as on neural-immune interactions in the hypothalamus. Cannabis has implications for psychosis. There are blunted psychotomimetic and amnestic effects with cannabis. Lithium increases oxytocin and helps in cannabis withdrawal, and pregnenolone/progesterone help in cannabis withdrawal as estrogen generally increases and progesterone decreases sensitivity to marijuana.
Cannabis and alcohol both increase alpha and theta sleep and decrease delta sleep. Cannabis and alcohol inhibit delta sleep needed for the night time brain housekeeping duties and increase luteinizing hormone so core body temperature does not drop for brain cells to shrink for 60% more space between brain cells for the cerebral spinal fluid to wash out toxins. Since pot inhibits delta sleep, it also inhibits growth hormone and also dehydrates you, so klotho is reduced. Cannabis causes kidney stones by reduced klotho. Klotho is anti tumor, anti dementia, inhibits arteriosclerosis, osteoporosis, and skin atrophy, so since cannabis inhibits klotho, aging is increased. Cannibis decreases sex hormones, increases stress hormones, impairs fertility, inhibits copulation, reduces oxytocin-the love and protection hormone.
Transparency: Moon Mother has each batch of CBD oil tested for potency (as well as residual solvents and other contaminants) by a third party. The third-party lab reports (COAs) are all available on the website. We wouldn’t mind seeing a bit more information on the company itself on the website, but most of the important information is easy to find.
One study suggested that a dose of concentrated CBD oil might cause cell death in breast cancer cells. One more study involving mice dealt with this particular cancer as well. Researchers concluded that CBD might inhibit aggressive breast cancer cells from spreading.CBD oil can be used to prevent cancer from spreading. Some scientific studies show that the CBD compound can help suppress the growth of cancer cells and promote their destruction.
It should not be surprising that results like these have been going on for years. Just like research shows cannabinoids are therapeutically effective against epilepsy, there is research suggesting they can eliminate cancers and control other serious diseases. And in practice, for epilepsy and these other conditions, the results are translating to humans. People have been reliably eliminating cancers for years and mitigating diseases like diabetes, Crohn’s, fibromyalgia, heart disease, chronic pain, multiple sclerosis, and more. This is as serious as it gets, and more attention must be brought to this issue.
Hempseed's amino acid profile is comparable to other sources of protein such as meat, milk, eggs and soy. Protein digestibility-corrected amino acid scores (PDCAAS), which attempt to measure the degree to which a food for humans is a "complete protein", were 0.49–0.53 for whole hemp seed, 0.46–0.51 for hempseed meal, and 0.63–0.66 for hulled hempseed.
The ability of CBD to have effects on the EDC (endocannabinoid system) and other nervous systems has influenced researchers to believe that CBD can provide benefits for neurological disorders. For example, studies are ongoing for the effectiveness of CBD against epilepsy. Presently, there is only one scenario where using cannabidiol treatment for epilepsy has significant scientific evidence.
So, if it’s not psychoactive, what exactly is hemp used for? Ever since the Neolithic Age when farmers in China first cultivated this plant, the use of hemp grew in order to fulfill many different needs people had through history. It is now used to make clothing, biofuels, foods, health products, body care products and even plastic composites. One source suggests that this “magical plant” is currently used to create more than 25 thousand different products – as many as petroleum. The U.S. hemp industry was estimated to be worth around 500 million USD in annual retail sales in 2012, and this number is quickly trending upward, according to Hemp Industries Association.
In one survey, parents of children who suffer from treatment-resistant epilepsy and use CBD were asked about the benefits. 19 parents were included, 84% of which said that CBD reduced the frequency of seizures. Two parents said that CBD completely resolved seizures. Parents also reported improved alertness, sleep, and mood. Some side effects were drowsiness and fatigue [R].